ZETTOC HISTORYOver 60 years of bringing health and happiness

1954
Founded as Nippon Zeola Co., Ltd. in Setagaya-ku,
Tokyo, and developed Zeola toothpaste with zeolite,
a tartar-prevention agent.
1957
Launched Zettoc’s first brand,
Namban, a beauty cream.
1964
Technical partnership with Mennen of
the United States (presently Colgate-Palmolive)
to develop skincare products for men and babies.
1967
Technical partnership with Taisho Pharmaceutical
to develop Eagle,
a medicated toothpaste with vitamin E.
1968
Head office relocated to Marunouchi,
Chiyoda-ku, Tokyo, and plant relocated
to Fuchinobe, Sagamihara, Kanagawa.
1969
Developed Bath Charmin, a liquid medicated bath agent, for
Wakamoto Pharmaceutical.
1974
Technical partnership with Zenyaku Kogyo
to develop the first functional toothpaste in Japan
with lysozyme chloride (patented), and develop
the anti-inflammation enzyme toothpaste DenCure.
1977
Technical partnership
with Pigeon to develop a series
of skincare products for babies,
expanding our production
to include baby products.
1978
Developed RomoCoat, a mild,
low-acidity amino acid-based cream soap, for Zenyaku Kogyo.
Provided technical guidance on toothpastes
to Horen Industrial of Taiwan.
1986
Developed foam-type body soap AwaFresh for Sanyo Scott.
1990
Company name changed to
Nippon Zettoc Co., Ltd., and head office
relocated to Kudan, Chiyoda-ku, Tokyo.
1993
After 15 years of clinical testing, received approval from
the Central Pharmaceutical Affairs Council of the Ministry of Health,
Labor and Welfare for medicated hydroxyapatite,
developed jointly with Sangi. Apagard M toothpaste,
featuring this new effective ingredient,
is widely recognized in the market.
1995
Production of toothpastes increased
after success of Apagard M,
with production lines expanded and fully automated.
2002
Launched Zettoc’s own brand,
a new line of Pommier skincare products, used our method
of the proprietary emulsion manufacturing.
Developed Dentwell non-aqueous toothpaste with vitamin C,
the first of its type in the world,
for Taisho Pharmaceutical, and began production.
2004
Certified under the ISO9001:2000 quality management system (later transitioned to ISO9001:2008).
2005
Launched our own brand, MediCial, a series of skincare products
with vitamin C. Developed AvanBeads toothpaste
with lactobacillus, the first of its kind in Japan,
for Wakamoto Pharmaceutical.
2008
Plant relocated to Oyama-cho, Midori-ku,
Sagamihara, Kanagawa.
2010
Opened Shanghai Sales Office,
our first overseas office.
2012
Established Zettoc Trading Shanghai Co., Ltd.
as a local subsidiary.
Opened Osaka Office
in Azuchi-machi, Chuo-ku, Osaka.
2013
Certified under the Eco Action 21
environmental management standard.
2014
Our second factory constructed in
Sagamihara for pharmaceutical manufacturing.
Licensed for pharmaceutical manufacturing
and sales. Head office relocated to Shinjuku
Nomura Building, Shinjuku-ku, Tokyo.

OUR MAJOR PARTNERS

  • EN Otsuka Pharmaceutical Co., Ltd.
  • (株)イシュア
  • エイコー化成(株)
  • Ebisu Co., Ltd.
  • Osaki Medical Corporation
  • OG CORPORATION
  • Kaminomoto Co.,Ltd.
  • Kobayashi Pharmaceutical Co., Ltd.
  • Combi Corporation
  • SANGI CO.,LTD.
  • Ci Medical Co.,Ltd.
  • Shionogi & Co., Ltd.
  • GC Corporation
  • JPS pharmaceutical CO.,LTD.
  • SHOFU INC.
  • SHOWA YAKUHIN KAKO CO., LTD.
  • Zenyaku Kogyo Co., Ltd.
  • Taisho Pharmaceutical Co., Ltd.
  • DAIICHI SANKYO HEALTHCARE
    CO., LTD.
  • Takasago Aromas Corporation
  • Tampei PharmaceuticalCo.,Ltd.
  • TOKYO ALOE CO.,LTD.
  • (株)東京美容科学研究所
  • Nippon Shika Yakuhin Co.,Ltd.
  • 日本自然食品(有)
  • NatureLab. Co., Ltd.
  • Panasonic Corporation
  • Bean Stalk Snow Co.,Ltd.
  • Pigeon Corporation
  • FEED Corporation
  • HEIWA MEDIC inc.
  • love labo inc.
  • WAKAMOTO Co., Ltd.
  • (株)和漢製薬研究所
  • (五十音順)